Open AccessLine-field confocal optical coherence tomography for three-dimensional skin imaging
Author(s) -
Jonas Ogien,
Anthony Daures,
Maxime Cazalas,
JeanLuc Perrot,
Arnaud Dubois
Publication year - 2020
Publication title -
frontiers of optoelectronics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.538
H-Index - 19
eISSN - 2095-2767
pISSN - 2095-2759
DOI - 10.1007/s12200-020-1096-x
Subject(s) - optical coherence tomography , optics , supercontinuum , confocal , physics , laser , microscope , tomography , computer science , optical fiber , photonic crystal fiber
This paper reports on the latest advances in line-field confocal optical coherence tomography (LC-OCT), a recently invented imaging technology that now allows the generation of either horizontal (x × y) section images at an adjustable depth or vertical (x × z) section images at an adjustable lateral position, as well as three-dimensional images. For both two-dimensional imaging modes, images are acquired in real-time, with real-time control of the depth and lateral positions. Three-dimensional (x × y × z) images are acquired from a stack of horizontal section images. The device is in the form of a portable probe. The handle of the probe has a button and a scroll wheel allowing the user to control the imaging modes. Using a supercontinuum laser as a broadband light source and a high numerical microscope objective, an isotropic spatial resolution of ∼1 µm is achieved. The field of view of the three-dimensional images is 1.2 mm × 0.5 mm × 0.5 mm (x × y × z). Images of skin tissues are presented to demonstrate the potential of the technology in dermatology.