Open AccessGlioblastoma Metastasis to Parotid Gland and Neck Lymph Nodes: Fine-Needle Aspiration Cytology with Histopathologic Correlation
Author(s) -
Alfredo RomeroRojas,
Julio A. Díaz-Pérez,
Deirdre Amaro,
Alfonso Lozano-Castillo,
Sandra Isabel Chinchilla-Olaya
Publication year - 2013
Publication title -
head and neck pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.801
H-Index - 50
eISSN - 1936-0568
pISSN - 1936-055X
DOI - 10.1007/s12105-013-0448-x
Subject(s) - parotid gland , medicine , pathology , cervical lymph nodes , metastasis , lymph , cytology , salivary gland , fine needle aspiration cytology , parotidectomy , fine needle aspiration , immunohistochemistry , radiology , biopsy , cancer
Glioblastoma (GBM) is one of the most highly aggressive neoplasms of the central nervous system. Extra-cranial metastases in GBM are rare. Here we present the case of a 26-year-old man with extra-cranial metastasis of a frontal lobe GBM to the parotid gland, cervical lymph nodes, and bones, with initial diagnosis made by fine needle aspiration cytology (FNAC) of the parotid gland. FNAC is a reliable technique in the study of primary and secondary parotid gland neoplasms, allowing a presumptive diagnosis in difficult cases. We correlate the cytologic, histopathologic, and immunohistochemical findings in this case and discuss previous literature reports.