Open AccessDisintegrin and metalloproteinases (ADAMs) expression in gastroesophageal reflux disease and in esophageal adenocarcinoma
Author(s) -
Tuuli Kauttu,
Harri Mustonen,
Sanna Vainionpää,
Leena Krogerus,
Ilkka Ilonen,
Jari Räsänen,
Jarmo Salo,
Pauli Puolakkainen
Publication year - 2016
Publication title -
clinical and translational oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.902
H-Index - 48
eISSN - 1699-3055
pISSN - 1699-048X
DOI - 10.1007/s12094-016-1503-3
Subject(s) - medicine , reflux , matrix metalloproteinase , disintegrin , esophageal adenocarcinoma , disease , adenocarcinoma , gastroenterology , metalloproteinase , cancer
Clinically useful marker molecules for the progression of gastroesophageal reflux disease and Barrett's esophagus (BE) to esophageal adenocarcinoma (EAC) are lacking. Many adenocarcinomas and inflammatory conditions exhibit increased expression of ADAMs, 'a disintegrin and metalloproteinases'.
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