Open AccessAn early history of CCN2/CTGF research: the road to CCN2 via hcs24, ctgf , ecogenin, and regenerin
Author(s) -
Takigawa Masaharu
Publication year - 2018
Publication title -
journal of cell communication and signaling
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.329
H-Index - 44
eISSN - 1873-961X
pISSN - 1873-9601
DOI - 10.1007/s12079-017-0414-6
Subject(s) - ctgf , field (mathematics) , principal (computer security) , medicine , computer science , growth factor , mathematics , computer security , receptor , pure mathematics
The principal aim of this historical review is to present the processes by which the different aspects of CCN2/CTGF/Hcs24 were discovered by different groups and how much CCN2/CTGF, by being integrated into CCN family, has contributed to the establishment of the basic concepts regarding the role and functions of this new class of proteins. This review should be particularly useful to new investigators who have recently entered this exciting field of study and also provides a good opportunity to acknowledge the input of those individuals who participated in the development of this scientific field.