Open AccessStructural Characterization and Immunogenicity in Wild-Type and Immune Tolerant Mice of Degraded Recombinant Human Interferon Alpha2b
Author(s) -
Suzanne Hermeling,
L Aranha,
J Damen,
Monique Slijper,
Huub Schellekens,
Daan J.A. Crommelin,
Wim Jiskoot
Publication year - 2005
Publication title -
pharmaceutical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.815
H-Index - 206
eISSN - 1573-904X
pISSN - 0724-8741
DOI - 10.1007/s11095-005-8177-9
Subject(s) - chemistry , immunogenicity , gel electrophoresis , microbiology and biotechnology , circular dichroism , biochemistry , immune system , biology , immunology
This study was conducted to study the influence of protein structure on the immunogenicity in wild-type and immune tolerant mice of well-characterized degradation products of recombinant human interferon alpha2b (rhIFNalpha2b).
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom