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Complete mitogenome of Kashmir musk deer (Moschus cupreus) and its comparative phylogenetic relationships
Author(s) -
Bhim Singh,
Kumudani Bala Gautam,
Subhashree Sahoo,
Ajit Kumar,
Sandeep Kumar Gupta
Publication year - 2020
Publication title -
molecular biology reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.532
H-Index - 71
eISSN - 1573-4978
pISSN - 0301-4851
DOI - 10.1007/s11033-020-06002-4
Subject(s) - biology , phylogenetic tree , mitochondrial dna , lineage (genetic) , zoology , threatened species , phylogenetics , evolutionary biology , ecology , gene , genetics , habitat
Kashmir musk deer, Moschus cupreus (KMD) is one the most threatened species endemic to the Himalayan region of Kashmir, Pakistan and Afghanistan. Herein, we have sequenced, annotated and characterized the complete mitogenome of M. cupreus. The investigation and comparison of the mitogenome provide crucial information for phylogenetic analysis to understand the evolutionary relationships. The mitogenome of KMD was 16,354 bp long, comprising 13 protein-coding genes (PCGs), 22 transfer RNA genes (tRNAs), two ribosomal RNA genes (rRNAs) and non-coding control region. Its composition was highly A+T biased 68.42%, and exhibited a positive AT-skew (0.082) and negative GC-skew (- 0.307). The phylogenetic analysis suggested that KMD was a primitive and extant species in the genus Moschus, whereas Alpine musk deer (M. chrysogaster) and Himalayan musk deer (M. leucogaster) were the closest relatives. It indicated the placement of M. cupreus within the monotypic family Moschidae of musk deer. Hence, it provides a better understanding of lineage identification and musk deer evolution for further research.

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