Open AccessAssociation of C-peptide and leptin with prostate cancer incidence in the Health Professionals Follow-up Study
Author(s) -
Gabriel Y. Lai,
Edward L. Giovannucci,
Michaël Pollak,
Sarah B. Peskoe,
Meir J. Stampfer,
W. C. Willett,
Elizabeth A. Platz
Publication year - 2014
Publication title -
cancer causes and control
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.073
H-Index - 134
eISSN - 1573-7225
pISSN - 0957-5243
DOI - 10.1007/s10552-014-0369-3
Subject(s) - hyperinsulinemia , medicine , leptin , prostate cancer , body mass index , c peptide , odds ratio , endocrinology , cancer , quartile , insulin , confidence interval , oncology , insulin resistance , obesity
Hyperinsulinemia is hypothesized to influence prostate cancer risk. Thus, we evaluated the association of circulating C-peptide, which is a marker of insulin secretion, and leptin, which is secreted in response to insulin and influences insulin sensitivity, with prostate cancer risk.
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