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The natural history of multiple sclerosis
Author(s) -
George C. Ebers
Publication year - 2000
Publication title -
neurological sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.767
H-Index - 71
eISSN - 1590-3478
pISSN - 1590-1874
DOI - 10.1007/s100720070018
Subject(s) - natural history , multiple sclerosis , observational study , medicine , neurology , cohort , neuroradiology , neurosurgery , cohort study , population , clinical trial , intensive care medicine , pediatrics , psychiatry , environmental health
The natural history of chronic diseases is generally poorly understood. Multiple sclerosis is one of the best-studied diseases and we outline here some of the information obtained from 25,000 patient-years of observation. This population-based cohort received almost no treatment and certainly none known to alter the long-term natural course of the illness. There is a possibility that such data will prove useful in new generation clinical trials which are observational in nature.

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