Evidence for hyperprolactinemia in migraineurs: a systematic review and meta-analysis | Zendy

Ali Noori-Zadeh | Zendy; Morvarid Karamkhani | Zendy; Ali SeidkhaniNahal | Zendy; Afra Khosravi | Zendy; Shahram Darabi | Zendy

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Evidence for hyperprolactinemia in migraineurs: a systematic review and meta-analysis

Author(s) -

Ali Noori-Zadeh,

Morvarid Karamkhani,

Ali SeidkhaniNahal,

Afra Khosravi,

Shahram Darabi

Publication year - 2019

Publication title -

neurological sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.767

H-Index - 71

eISSN - 1590-3478

pISSN - 1590-1874

DOI - 10.1007/s10072-019-04035-7

Subject(s) - migraine , prolactin , meta analysis , medicine , strictly standardized mean difference , inclusion and exclusion criteria , neurology , pathogenesis , physiology , hormone , pathology , psychiatry , alternative medicine

One of the hypothalamus-pituitary axis hormones which may play a crucial role in pathophysiology of migraine is prolactin which is secreted from anterior pituitary gland and synthesized by various immune system cells as well. Whether prolactin blood levels can affect the migraine pathogenesis is an open question. Therefore, investigating prolactin circulatory levels in migraineurs may pave the way to underpin the mechanisms of migraine pathophysiology at biochemical levels. In the current investigation, the prolactin blood levels in the migraine subjects were investigated using systematic review and meta-analysis.

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