Xenogeneic bone filling materials modulate mesenchymal stem cell recruitment: role of the Complement C5a | Zendy

Charlotte Jeanneau | Zendy; Chloé Le Fournis | Zendy; Imad About | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Xenogeneic bone filling materials modulate mesenchymal stem cell recruitment: role of the Complement C5a

Author(s) -

Charlotte Jeanneau,

Chloé Le Fournis,

Imad About

Publication year - 2019

Publication title -

clinical oral investigations

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.088

H-Index - 82

eISSN - 1436-3771

pISSN - 1432-6981

DOI - 10.1007/s00784-019-03087-5

Subject(s) - mesenchymal stem cell , complement (music) , stem cell , medicine , microbiology and biotechnology , biology , phenotype , genetics , complementation , gene

When bone filling materials are applied onto the periodontal tissues in vivo, they interact with the injured periodontal ligament (PDL) tissue and modulate its activity. This may lead to mesenchymal stem cells (MSCs) recruitment from bone marrow and initiate bone regeneration. Our hypothesis is that the filling materials affect PDL cells and MSCs functional activities by modulating PDL C5a secretion and subsequent MSCs proliferation and recruitment.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research