The accumulation of regulatory T cells in the hepatic hilar lymph nodes in biliary atresia | Zendy

Naoya Sakamoto | Zendy; Toshihiro Muraji | Zendy; Haruo Ohtani | Zendy; Kouji Masumoto | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

The accumulation of regulatory T cells in the hepatic hilar lymph nodes in biliary atresia

Author(s) -

Naoya Sakamoto,

Toshihiro Muraji,

Haruo Ohtani,

Kouji Masumoto

Publication year - 2017

Publication title -

surgery today

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.655

H-Index - 63

eISSN - 1436-2813

pISSN - 0941-1291

DOI - 10.1007/s00595-017-1502-1

Subject(s) - medicine , surgical oncology , biliary atresia , lymph , general surgery , pathology , gastroenterology , liver transplantation , transplantation

A proposed etiopathogenesis of biliary atresia (BA) involves T-cell-mediated inflammatory bile duct damage and progressive hepatic fibrosis. Pediatric surgeons often observe swelling of the hepatic hilar lymph nodes during the Kasai procedure. Given the importance of regulatory mechanisms in immune responses, the present study was designed to analyze the quantitative changes of regulatory T cells (T reg cells) in the hepatic hilar lymph nodes (hepatic hilar LNs) and peripheral blood (PB) in BA.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research