Open AccessAn increased number of PD-1+ and Tim-3+ CD8+ T cells is involved in immune evasion in gastric cancer
Author(s) -
Shuichi Takano,
Hiroaki Saito,
Masahide Ikeguchi
Publication year - 2016
Publication title -
surgery today
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.655
H-Index - 63
eISSN - 1436-2813
pISSN - 0941-1291
DOI - 10.1007/s00595-016-1305-9
Subject(s) - cd8 , immune system , cytotoxic t cell , medicine , cancer , flow cytometry , peripheral blood mononuclear cell , cancer cell , immunology , cancer research , biology , in vitro , biochemistry
Co-signaling molecules play an important role in T cells. This study was designed to investigate PD-1 and Tim-3 expression on T cells and the relationships between PD-1 and Tim-3 expression and immune evasion in patients with gastric cancer.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom