ITPA polymorphism effects on decrease of hemoglobin during sofosbuvir and ribavirin combination treatment for chronic hepatitis C | Zendy

Kei Morio | Zendy; Michio Imamura | Zendy; Yoshiiku Kawakami | Zendy; Takashi Nakahara | Zendy; Yuko Nagaoki | Zendy; Tomokazu Kawaoka | Zendy; Masataka Tsuge | Zendy; Akira Hiramatsu | Zendy; Hiroshi Aikata | Zendy; C. Nelson Hayes | Zendy; Grace Naswa Makokha | Zendy; Hidenori Ochi | Zendy; Hajime Amano | Zendy; Keiko Arataki | Zendy; Takashi Moriya | Zendy; Hiroyuki Ito | Zendy; Keiji Tsuji | Zendy; Hiroshi Kohno | Zendy; Koji Waki | Zendy; Toru Tamura | Zendy; Toshio Nakamura | Zendy; Kazuaki Chayama | Zendy

Open Access

ITPA polymorphism effects on decrease of hemoglobin during sofosbuvir and ribavirin combination treatment for chronic hepatitis C

Author(s) -

Kei Morio,

Michio Imamura,

Yoshiiku Kawakami,

Takashi Nakahara,

Yuko Nagaoki,

Tomokazu Kawaoka,

Masataka Tsuge,

Akira Hiramatsu,

Hiroshi Aikata,

C. Nelson Hayes,

Grace Naswa Makokha,

Hidenori Ochi,

Hajime Amano,

Keiko Arataki,

Takashi Moriya,

Hiroyuki Ito,

Keiji Tsuji,

Hiroshi Kohno,

Koji Waki,

Toru Tamura,

Toshio Nakamura,

Kazuaki Chayama

Publication year - 2016

Publication title -

journal of gastroenterology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.33

H-Index - 114

eISSN - 1435-5922

pISSN - 0944-1174

DOI - 10.1007/s00535-016-1279-9

Subject(s) - itpa , ribavirin , sofosbuvir , medicine , gastroenterology , pegylated interferon , hepatology , hepatitis c virus , genotype , immunology , biology , virus , genetics , gene

Polymorphisms in the inosine triphosphatase (ITPA) gene is associated with anemia induced by peg-interferon (PEG-IFN) plus ribavirin (RBV) treatment for patients with chronic hepatitis C virus (HCV) infection. However, the effect of ITPA polymorphism on sofosbuvir plus RBV treatment is unknown.

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