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Renal dysfunction and hypophosphatemia during long-term lamivudine plus adefovir dipivoxil therapy in patients with chronic hepatitis B
Author(s) -
Mio Tanaka,
Fumitaka Suzuki,
Yuya Seko,
Tasuku Hara,
Yusuke Kawamura,
Hitomi Sezaki,
Tetsuya Hosaka,
Norio Akuta,
Masahiro Kobayashi,
Yoshiyuki Suzuki,
Satoshi Saitoh,
Yasuji Arase,
Kenji Ikeda,
Mariko Kobayashi,
Hiromitsu Kumada
Publication year - 2013
Publication title -
journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.33
H-Index - 114
eISSN - 1435-5922
pISSN - 0944-1174
DOI - 10.1007/s00535-013-0779-0
Subject(s) - hypophosphatemia , adefovir , medicine , lamivudine , gastroenterology , renal function , creatinine , hepatology , fanconi syndrome , kidney , hepatitis b virus , immunology , virus
Renal dysfunction and Fanconi's syndrome associated with hypophosphatemia caused by long-term administration of low-dose adefovir dipivoxil (ADV) has been reported in recent years. The aim of this retrospective study was to determine the incidence and factors associated with renal dysfunction and hypophosphatemia in patients with hepatitis B infection on long-term treatment with ADV and lamivudine (LAM).

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