NOD2 gene mutations in ulcerative colitis: useless or misunderstood? | Zendy

Paulo Freire | Zendy; Ricardo Cardoso | Zendy; Pedro Figueiredo | Zendy; Maria Manuel Donato | Zendy; Manuela Ferreira | Zendy; Sofia Mendes | Zendy; Ana Margarida Ferreira | Zendy; M. Helena Vasconcelos | Zendy; Francisco Portela | Zendy; Carlos Sofia | Zendy

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NOD2 gene mutations in ulcerative colitis: useless or misunderstood?

Author(s) -

Paulo Freire,

Ricardo Cardoso,

Pedro Figueiredo,

Maria Manuel Donato,

Manuela Ferreira,

Sofia Mendes,

Ana Margarida Ferreira,

M. Helena Vasconcelos,

Francisco Portela,

Carlos Sofia

Publication year - 2014

Publication title -

international journal of colorectal disease

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.831

H-Index - 88

eISSN - 1432-1262

pISSN - 0179-1958

DOI - 10.1007/s00384-014-1850-x

Subject(s) - ulcerative colitis , nod2 , medicine , gastroenterology , genotype , colectomy , crohn's disease , mutation , disease , gene , genetics , biology

NOD2 mutations have been linked to an increased risk of Crohn's disease and to some of its phenotypes. The association between NOD2 mutations and susceptibility to ulcerative colitis (UC) remains somewhat controversial and potential correlations between these mutations and UC phenotype have not been studied.

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