Single-strand gap repair involves both RecF and RecBCD pathways | Zendy

Vincent Pagès | Zendy

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Single-strand gap repair involves both RecF and RecBCD pathways

Author(s) -

Vincent Pagès

Publication year - 2016

Publication title -

current genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.825

H-Index - 81

eISSN - 1432-0983

pISSN - 0172-8083

DOI - 10.1007/s00294-016-0575-5

Subject(s) - recbcd , homologous recombination , biology , dna repair , single strand , dna , homologous chromosome , recombination , double strand , genetics , microbiology and biotechnology , computational biology , gene

Homologous recombination repairs discontinuities in DNA including single-strand gaps (SSGs) and double-strand breaks (DSBs). This commentary describes how the RecBCD and RecF pathways might be exchangeable for the repair of their respective DSB and SSG canonical substrates. In particular, I will discuss how the RecBCD pathway could engage in the repair of an SSG even when the latter is not associated with a DSB.

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