Open AccessIntraoperative Nerve Monitoring Can Reduce Prevalence of Recurrent Laryngeal Nerve Injury in Thyroid Reoperations: Results of a Retrospective Cohort Study
Author(s) -
Barczyński Marcin,
Konturek Aleksander,
Pragacz Krzysztof,
Papier Aleksandra,
Stopa Małgorzata,
Nowak Wojciech
Publication year - 2014
Publication title -
world journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.115
H-Index - 148
eISSN - 1432-2323
pISSN - 0364-2313
DOI - 10.1007/s00268-013-2260-x
Subject(s) - medicine , recurrent laryngeal nerve , thyroid , surgery , retrospective cohort study , thyroidectomy , thyroid cancer , nerve injury , dissection (medical) , abdominal surgery , goiter
Background The prevalence of recurrent laryngeal nerve (RLN) injury is higher in repeat than in primary thyroid operations. The use of intraoperative nerve monitoring (IONM) as an aid in dissection of the scar tissue is believed to minimize the risk of nerve injury. The aim of this study was to examine whether the use of IONM in thyroid reoperations can reduce the prevalence of RLN injury. Methods This was a retrospective cohort study of patients who underwent thyroid reoperations with IONM versus with RLN visualization, but without IONM. The database of thyroid surgery was searched for eligible patients (treated in the years 1993–2012). The primary outcomes were transient and permanent RLN injury. Laryngoscopy was used to evaluate and follow RLN injury. Results The study group comprised 854 patients (139 men, 715 women) operated for recurrent goiter ( n = 576), recurrent hyperthyroidism ( n = 36), completion thyroidectomy for cancer ( n = 194) or recurrent thyroid cancer ( n = 48), including 472 bilateral and 382 unilateral reoperations; 1,326 nerves at risk (NAR). A group of 306 patients (500 NAR) underwent reoperations with IONM and 548 patients (826 NAR) had reoperations with RLN visualization, but without IONM. Transient and permanent RLN injuries were found respectively in 13 (2.6 %) and seven (1.4 %) nerves with IONM versus 52 (6.3 %) and 20 (2.4 %) nerves without IONM ( p = 0.003 and p = 0.202, respectively). Conclusions IONM decreased the incidence of transient RLN paresis in repeat thyroid operations compared with nerve visualization alone. The prevalence of permanent RLN injury tended to be lower in thyroid reoperations with IONM, but statistical validation of the observed differences requires a sample size of 920 NAR per arm.