Peripheral inflammation is associated with brain SPECT perfusion changes in schizophrenia | Zendy

Guillaume Fond | Zendy; Alexandra Garosi | Zendy; Mélanie Faugère | Zendy; JacquesYves Campion | Zendy; Christophe Lançon | Zendy; Laurent Boyer | Zendy; Raphaëlle Richieri | Zendy; Éric Guedj | Zendy

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Peripheral inflammation is associated with brain SPECT perfusion changes in schizophrenia

Author(s) -

Guillaume Fond,

Alexandra Garosi,

Mélanie Faugère,

JacquesYves Campion,

Christophe Lançon,

Laurent Boyer,

Raphaëlle Richieri,

Éric Guedj

Publication year - 2021

Publication title -

european journal of nuclear medicine and molecular imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.313

H-Index - 163

eISSN - 1619-7089

pISSN - 1619-7070

DOI - 10.1007/s00259-021-05529-3

Subject(s) - medicine , perfusion , superior temporal gyrus , schizophrenia (object oriented programming) , perfusion scanning , peripheral , cardiology , antipsychotic , postcentral gyrus , magnetic resonance imaging , psychiatry , radiology , functional magnetic resonance imaging

Peripheral inflammation is frequent in schizophrenia and could play a role in the pathophysiology, prognosis, and persistence of psychotic symptomatology under treatment. We seek to determine the relationship between peripheral inflammation and brain SPECT perfusion in stabilized antipsychotic-treated outpatients with schizophrenia, and to determine whether such perfusion changes are correlated with persistent symptoms.

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