From metabolic connectivity to molecular connectivity: application to dopaminergic pathways | Zendy

Antoine Verger | Zendy; Tatiana Horowitz | Zendy; Mohammad B. Chawki | Zendy; Alexandre Eusébio | Zendy; Ma Bordonné | Zendy; JeanPhilippe Azulay | Zendy; Nadine Girard | Zendy; Éric Guedj | Zendy

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From metabolic connectivity to molecular connectivity: application to dopaminergic pathways

Author(s) -

Antoine Verger,

Tatiana Horowitz,

Mohammad B. Chawki,

Alexandre Eusébio,

Ma Bordonné,

JeanPhilippe Azulay,

Nadine Girard,

Éric Guedj

Publication year - 2019

Publication title -

european journal of nuclear medicine and molecular imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.313

H-Index - 163

eISSN - 1619-7089

pISSN - 1619-7070

DOI - 10.1007/s00259-019-04574-3

Subject(s) - voxel , dopaminergic , nuclear medicine , positron emission tomography , neuroscience , standardized uptake value , medicine , chemistry , dopamine , psychology , radiology

This study aims to reveal the feasibility and potential of molecular connectivity based on neurotransmission in comparison with the metabolic connectivity with an application to dopaminergic pathways. For this purpose, we propose to compare the neurotransmission connectivity findings using 123 I-FP-CIT SPECT and 18 F-FDOPA PET with the metabolic connectivity findings using 18 F-FDG PET.

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