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Use of FDG PET/CT for investigation of febrile neutropenia: evaluation in high-risk cancer patients
Author(s) -
Stephen Guy,
Adrian R Tramontana,
Leon J. Worth,
Eddie Lau,
Rodney J. Hicks,
John F. Seymour,
Karin Thursky,
Monica A. Slavin
Publication year - 2012
Publication title -
european journal of nuclear medicine and molecular imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.313
H-Index - 163
eISSN - 1619-7089
pISSN - 1619-7070
DOI - 10.1007/s00259-012-2143-7
Subject(s) - medicine , neutropenia , fever of unknown origin , febrile neutropenia , malignancy , cancer , radiology , positron emission tomography , nuclear medicine , chemotherapy
Febrile neutropenia (FNP) is a frequent complication of cancer care and evaluation often fails to identify a cause. [(18) F]FDG PET/CT has the potential to identify inflammatory and infectious foci, but its potential role as an investigation for persistent FNP has not previously been explored. The aim of this study was to prospectively evaluate the clinical utility of FDG PET/CT in patients with cancer and severe neutropenia and five or more days of persistent fever despite antibiotic therapy.

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