Does Human mtDNA Recombine? | Zendy

Adam EyreWalker | Zendy; Philip Awadalla | Zendy

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Does Human mtDNA Recombine?

Author(s) -

Adam EyreWalker,

Philip Awadalla

Publication year - 2001

Publication title -

journal of molecular evolution

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.693

H-Index - 123

eISSN - 1432-1432

pISSN - 0022-2844

DOI - 10.1007/s002390010232

Subject(s) - biology , recombination , mitochondrial dna , population , genetics , genetic recombination , evolutionary biology , genome , gene , demography , sociology

In this article we review the evidence for and against recombination in human mtDNA. If recombination occurs, there needs to be a route by which genetic material can incorporate itself into the mitochondrial genome, and hence between mitochondrial lineages. We review the evidence for possible routes and then review the current state of the population genetic evidence for recombination. We conclude that there is no firmly established route by which recombination can occur, and that while some of the population genetic evidence is suggestive of recombination, it is far from conclusive.

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