Open AccessPharmacogenomic adaptation of antiretroviral therapy: overcoming the failure of lopinavir in an African infant with CYP2D6 ultrarapid metabolism
Author(s) -
Matthias Gorny,
Stephanie Röhm,
Stephanie Läer,
Nezihe Morali,
Tim Niehues
Publication year - 2009
Publication title -
european journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.845
H-Index - 108
eISSN - 1432-1041
pISSN - 0031-6970
DOI - 10.1007/s00228-009-0753-1
Subject(s) - pharmacogenomics , cyp2d6 , lopinavir , medicine , pharmacogenetics , pharmacology , biopharmaceutics , pharmacokinetics , lopinavir/ritonavir , antiretroviral therapy , metabolism , human immunodeficiency virus (hiv) , pharmacognosy , chemistry , cytochrome p450 , viral load , virology , genotype , biochemistry , biological activity , in vitro , gene
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