Evidence for immunological (allergic) mechanisms in a subgroup of patients with phenprocoumon-induced liver disease | Zendy

Reinhild Klein | Zendy

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Evidence for immunological (allergic) mechanisms in a subgroup of patients with phenprocoumon-induced liver disease

Author(s) -

Reinhild Klein

Publication year - 2009

Publication title -

european journal of clinical pharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.845

H-Index - 108

eISSN - 1432-1041

pISSN - 0031-6970

DOI - 10.1007/s00228-009-0705-9

Subject(s) - phenprocoumon , medicine , gastroenterology , drug , liver disease , peripheral blood mononuclear cell , immunology , side effect (computer science) , pharmacology , in vitro , chemistry , warfarin , atrial fibrillation , biochemistry , computer science , programming language

Phenprocoumon-induced liver injury is a rare complication of oral anticoagulation. The mechanisms leading to this side effect are not entirely clear. Here we present data that at least in a subgroup of patients in whom phenprocoumon-induced liver disease was suspected, immunological processes may play an important role.

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