Open AccessImpact of CYP2C19 phenotypes on escitalopram metabolism and an evaluation of pupillometry as a serotonergic biomarker
Author(s) -
Lene NoehrJensen,
Stine T. Zwisler,
Fin Stolze Larsen,
Søren H. Sindrup,
Per Damkier,
Flemming Nielsen,
Kim Brøsen
Publication year - 2009
Publication title -
european journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.845
H-Index - 108
eISSN - 1432-1041
pISSN - 0031-6970
DOI - 10.1007/s00228-009-0657-0
Subject(s) - serotonergic , escitalopram , cyp2c19 , pupillometry , biomarker , pharmacology , medicine , citalopram , metabolism , serotonin , biology , neuroscience , genetics , antidepressant , pupil , receptor , cytochrome p450 , hippocampus
To investigate the impact of cytochrome P450 2C19 (CYP2C19) phenotypes on escitalopram metabolism and to evaluate pupillometry as a serotonergic biomarker.
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