Glutathione-S-transferase-P1 I105V polymorphism and response to antenatal betamethasone in the prevention of respiratory distress syndrome
Author(s) -
Chiara Oretti,
Sara Marino,
Fabio Mosca,
Maria Rosa Colnaghi,
Sara De Iudicibus,
Ilenia Drigo,
Gabriele Stocco,
Fiora Bartoli,
Giuliana Decorti,
Sergio Demarini
Publication year - 2009
Publication title -
european journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.845
H-Index - 108
eISSN - 1432-1041
pISSN - 0031-6970
DOI - 10.1007/s00228-009-0617-8
Subject(s) - betamethasone , respiratory distress , genotype , medicine , gestation , biology , endocrinology , physiology , genetics , gene , pregnancy , anesthesia
The aim of this pilot study was to assess the association between polymorphisms in genes that encode for proteins involved in the pharmacokinetics/pharmacodynamics of glucocorticoids and the occurrence of respiratory distress syndrome (RDS) in preterm infants born to mothers treated with a complete course of betamethasone.
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