Open AccessNovel nano‐composite multi‐layered biomaterial for the treatment of multifocal degenerative cartilage lesions
Author(s) -
Kon Elizaveta,
Delcogliano M.,
Filardo G.,
Altadonna G.,
Marcacci M.
Publication year - 2009
Publication title -
knee surgery, sports traumatology, arthroscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.806
H-Index - 125
eISSN - 1433-7347
pISSN - 0942-2056
DOI - 10.1007/s00167-009-0819-8
Subject(s) - medicine , implant , patella , high tibial osteotomy , hyaline cartilage , cartilage , range of motion , osteoarthritis , anterior cruciate ligament , surgery , articular cartilage , anatomy , pathology , alternative medicine
We report on a 46‐year‐old athletic patient, previously treated with anterior cruciate ligament reconstruction, with large degenerative chondral lesions of the medial femoral condyle, trochlea and patella, which was successfully treated with a closing‐wedge high tibial osteotomy and the implant of a newly developed biomimetic nanostructured osteochondral bioactive scaffold. After 1 year of follow‐up the patient was pain‐free, had full knee range of motion, and had returned to his pre‐operation level of athletic activity. MRI evaluation at 6 months showed that the implant gave a hyaline‐like signal as well as a good restoration of the articular surface, with minimal subchondral bone oedema. Subchondral oedema was almost non‐visible at 12 months.