Chronic stress modulates the virus-specific immune response to latent herpes simplex virus Type 1 | Zendy

Ronald Glaser | Zendy; Janice K. KiecoltGlaser | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Chronic stress modulates the virus-specific immune response to latent herpes simplex virus Type 1

Author(s) -

Ronald Glaser,

Janice K. KiecoltGlaser

Publication year - 1997

Publication title -

annals of behavioral medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.701

H-Index - 133

eISSN - 1532-4796

pISSN - 0883-6612

DOI - 10.1007/bf02883323

Subject(s) - herpes simplex virus , immune system , immunology , neutralizing antibody , virology , antibody , virus , titer , antigen , antibody titer , latent virus , medicine

We compared 71 family caregivers of dementia sufferers and 58 control subjects on three different immune measures relevant to latent herpes simplex virus Type 1 (HSV-1) infection: neutralizing antibody titers, antibody titers to a total viral antigen, and a proliferative memory T-cell response. Caregivers had significantly higher antibody titers to the total viral antigen and a poorer HSV-1 specific T-cell response than controls, but no significant difference in neutralizing antibody titers between groups was observed. These data provide additional evidence that psychological stress can modulate a virus-specific immune response associated with caregiving.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research