The Nobel Prize in Chemistry 2004 | Zendy

Chandrakant S. Karigar | Zendy; K. R. Siddalinga Murthy | Zendy

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The Nobel Prize in Chemistry 2004

Author(s) -

Chandrakant S. Karigar,

K. R. Siddalinga Murthy

Publication year - 2005

Publication title -

resonance

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.173

H-Index - 13

ISSN - 0971-8044

DOI - 10.1007/bf02835891

Subject(s) - proteolysis , ubiquitin , chemistry , proteasome , microbiology and biotechnology , biochemistry , biophysics , computational biology , enzyme , biology , gene

The Nobel Prize in Chem. for 2004 is shared by Aaron Ciechanover, Avram Hershko and Irwin Rose, who made fundamental discoveries concerning how cells regulate the breakdown of cellular proteins with extreme specificity. The three biochemists discovered ubiquitin-mediated proteolysis, a process where an enzyme system tags unwanted proteins with many mols. of a small protein called ubiquitin and then sends then to the proteasome where they are broken down

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