Organic synthesis under solvent-free condition: An environmentally benign procedure — I

A review. The growing concern to minimize the environmental pollution caused by solvents and the increasing interest in solid-solid reactions have led to the development of methodologies for solvent-free reactions with considerable success. Solvent-free or solid state reaction may be carried out using the reactants alone or incorporating them in clays, zeolites, silica, alumina or other matrixes. The principles and disadvantages of solvent-free org. synthesis are discussed. Illustrative examples representing a no. of org. syntheses performed under both thermal and photochem. conditions are described