Open AccessImproved yield by cryoeffect in kinetically controlled peptide synthesis catalyzed with alcalase
Author(s) -
ShuiTein Chen,
Shiah-Yun Chen,
ChaiLin Kao,
KungTsung Wang
Publication year - 1994
Publication title -
biotechnology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.548
H-Index - 107
eISSN - 1573-6776
pISSN - 0141-5492
DOI - 10.1007/bf01022406
Subject(s) - catalysis , yield (engineering) , chemistry , enzyme , peptide , reaction conditions , enzyme catalysis , stereochemistry , combinatorial chemistry , organic chemistry , biochemistry , materials science , metallurgy
The yields of a kinetically controlled enzymatic reaction catalyzed by alcalase in alcohols increased 15%∼40% when the reaction temperature was 5 o C instead of 25-30 o C. High yields of biologically active pepbde intermediates were obtained from reaction at 5 o C
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