Open AccessAlcalase catalyzed peptide bond formation between Asp and D-Ala in anhydrous t-butanol
Author(s) -
ShuiTein Chen,
Sung-Yang Wu,
Shiah-Yun Chen,
KungTsung Wang
Publication year - 1993
Publication title -
biotechnology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.548
H-Index - 107
eISSN - 1573-6776
pISSN - 0141-5492
DOI - 10.1007/bf00128279
Subject(s) - anhydrous , catalysis , chemistry , protease , isopropyl , n butanol , butanol , peptide , alkaline protease , enzyme , organic chemistry , stereochemistry , chromatography , combinatorial chemistry , biochemistry , ethanol
Procedures for preparing precusors of the artificial sweetner, Moz-Asp(Bzl)- D-Ala-R, R=NH2, n-Propyl, isopropyl, in anhydrous t-butanol catalyzed by an industrial alkaline protease “alcalase” using a kinetic-controlled approach have been developed.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom