Manual of Clinical Oncology

I. General Aspects.- and Survey.- Induction Phase.- In Situ Phase.- Invasion Phase.- Dissemination Phase.- Conclusion.- Epidemiology.- Mortality and Incidence.- Aetiology.- Methods of Study Problems.- Ionizing Radiation.- Ultraviolet Radiation.- Air Pollution.- Occupational Factors.- Alimentary Factors.- Iatrogenic Chemical Factors.- Hormones.- Tobacco.- Alcohol.- Sex and Reproductive Life.- Circumcision.- Parasites.- Viruses.- Genetic Factors.- Immunodeficiency.- Conclusion.- Prevention.- Primary Prevention.- Secondary Prevention.- New Horizons.- Priorities for Action.- Pathology.- Definitions.- Classification.- Tumour Structure.- Grading.- In Situ and Pre-cancerous Lesions.- Role of Surgical Pathologist.- Natural History of Cancer.- Tumour Growth.- Tumour Spread.- Tumour-Host Relationship.- Local Recurrences and Metastases.- Multiple Primary Cancers.- Causes of Death.- Spontaneous Regression.- Mass Screening and Early Detection.- Cervical Cancer.- Breast Cancer.- Diagnosis.- History.- Physical Examination.- Special Procedures.- Delay in Diagnosis.- Evaluation of the Extent of Disease.- Clinical Staging.- Pathological Staging.- Anatomical Staging.- Principles of Treatment.- "Multidisciplinary" Team Approach to Cancer Therapy.- Planning the Treatment.- Forms of Treatment.- Surgery.- Radiation Therapy.- Chemotherapy.- Hormone Treatment.- Immunotherapy.- Evaluation of Response to Treatment.- Acute Problems in Cancer Management.- Supportive Care of Cancer Patients.- Rehabilitation.- Psychosocial Aspects.- The Physician's Attitude to Cancer.- The Patient's Attitude to His Cancer.- The Doctor-Patient Relationship.- The Special Problems of the "Dying Patient".- Education of the Public About Cancer.- Unproven Methods of Cancer Treatment.- Prognosis.- II. Cancers of Specific Sites.- Skin Cancer.- Melanoma.- Head and Neck.- General Aspects.- Lip.- Anterior Two-Thirds of Tongue (Mobile Portion of Tongue).- Floor of Mouth, Buccal Mucosa.- Gums and Hard Palate.- Tonsils.- Base of Tongue.- Soft Palate.- Nasopharynx.- Hypopharynx.- Nasal Fossa.- Paranasal Sinuses.- Glottic Larynx (Involving the True Vocal Cords).- Supraglottic Larynx.- Salivary Glands.- Chemodectomas.- Thyroid.- Tumours of the Eye.- Intraocular Tumours.- Conjunctival Tumours.- Thorax.- Lung.- Pleura.- Mediastinum.- Alimentary Tract.- Oesophagus.- Stomach.- Pancreas.- Liver.- Gall Bladder.- Colon, Rectum and Anus.- Breast.- Female Genital Organs.- Uterine Cervix.- Endometrium.- Choriocarcinoma.- Ovary.- Vagina.- Vulva.- Male Genital Organs.- Testis.- Penis.- Prostate.- Urinary Tract.- Kidney, Renal Pelvis, Ureter.- Renal Cell Carcinoma.- Carcinoma of Renal Pelvis and Ureter.- Nephroblastoma (Wilms' Tumour).- Bladder.- Central Nervous System.- Gliomas.- Tumours of the Membranes.- Embryoplastic Tumours.- Mesenchymal Tumours.- Tumours of the Spinal Cord.- Secondary Brain Tumours.- Bone and Soft Tissue.- Bone Tumours.- Osteogenic Sarcoma and Ewing's Sarcoma.- Chondrosarcoma.- Myeloma.- Soft Tissue Sarcomas.- Bone Sarcomas.- Lymphomas and Myeloma.- Multiple Myeloma.- Leukaemias.- Childhood Cancers.- Wilms' Tumour (Nephroblastoma).- Neuroblastoma.- Rhabdomysarcoma.- III. Basic Science Research of Imminent Impact on Clinical Oncology.- Cancer Diagnosis.- Biomarkers.- Digital Subtraction Angiography.- Magnetic Resonance Imaging.- Radiolabelled Monoclonal Antibodies.- Oncogenes and Human Neoplasia.- Recombinant DNA Technology.- Cancer Therapy.- Laser Therapy.- Intraoperative Radiation Therapy.- Tumour Stem Cell Assays.- Autologous Bone Marrow Transplantation.- Drug Delivery Systems.- Lymphokines in the Treatment of Cancer.- Acquired Immune Deficiency Syndrome.- References.