Information Processign in Cells and Tissues
Author(s) -
Michael A. Lones,
Stephen L. Smith,
Sarah A. Teichmann,
Félix Naef,
James A. Walker,
Martin A. Trefzer
Publication year - 2012
Publication title -
lecture notes in computer science
Language(s) - English
Resource type - Book series
SCImago Journal Rank - 0.249
H-Index - 400
eISSN - 1611-3349
pISSN - 0302-9743
DOI - 10.1007/978-3-642-28792-3
Subject(s) - computer science , chemistry
Artificial gene regulatory networks are computational models which draw inspiration from real world networks of biological gene regulation. Since their inception they have been used to infer knowledge about gene regulation and as methods of computation. These computational models have been shown to possess properties typically found in the biological world such as robustness and self organisation. Recently, it has become apparent that epigenetic mechanisms play an important role in gene regulation. This paper introduces a new model, the Artificial Epigenetic Regulatory Network (AERN) which builds upon existing models by adding an epigenetic control layer. The results demonstrate that the AERNs are more adept at controlling multiple opposing trajectories within Chirikov’s standard map, suggesting that AERNs are an interesting area for further investigation.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom