Frequent Subsequence-Based Protein Localization

Extracellular plant proteins are involved in numerous pro- cesses including nutrient acquisition, communication with other soil organisms, protection from pathogens, and resistance to disease and toxic metals. Insofar as these proteins are strategically positioned to play a role in resistance to environmental stress, biologists are interested in proteomic tools in analyzing extracellular proteins. In this paper, we present three methods using frequent subsequences of amino acids: one based on support vector machines (SVM), one based on boosting and FSP, a new frequent subsequence pattern method. We test our methods on a plant dataset and the experimental results show that our methods perform better than the existing approaches based on amino acid composition.