Bayesian Sequence Learning for Predicting Protein Cleavage Points
Author(s) -
Michael Mayo
Publication year - 2005
Publication title -
lecture notes in computer science
Language(s) - English
Resource type - Book series
SCImago Journal Rank - 0.249
H-Index - 400
eISSN - 1611-3349
pISSN - 0302-9743
ISBN - 3-540-26076-5
DOI - 10.1007/11430919_25
Subject(s) - computer science , artificial intelligence , artificial neural network , sequence (biology) , bayesian probability , data mining , machine learning , bayesian network , state (computer science) , pattern recognition (psychology) , algorithm , genetics , biology
A challenging problem in data mining is the application of efficient techniques to automatically annotate the vast databases of biological sequence data. This paper describes one such application in this area, to the prediction of the position of signal peptide cleavage points along protein sequences. It is shown that the method, based on Bayesian statistics, is comparable in terms of accuracy to the existing state-of-the-art neural network techniques while providing explanatory information for its predictions
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