Open AccessRegen med therapeutic opportunities for fighting COVID ‐19
Author(s) -
Atala Anthony,
Henn Alicia,
Lundberg Martha,
Ahsan Taby,
Greenberg Jordan,
Krukin Jeff,
Lynum Steven,
Lutz Cat,
Cetrulo Kyle,
Albanna Mohammad,
Pereira Taciana,
Eaker Shan,
Hunsberger Joshua
Publication year - 2021
Publication title -
stem cells translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.781
H-Index - 71
eISSN - 2157-6580
pISSN - 2157-6564
DOI - 10.1002/sctm.20-0245
Subject(s) - covid-19 , regenerative medicine , battle , pandemic , personalized medicine , perspective (graphical) , medicine , intensive care medicine , engineering ethics , stem cell , bioinformatics , biology , computer science , virology , pathology , engineering , infectious disease (medical specialty) , disease , history , archaeology , artificial intelligence , outbreak , genetics
This perspective from a Regenerative Medicine Manufacturing Society working group highlights regenerative medicine therapeutic opportunities for fighting COVID‐19. This article addresses why SARS‐CoV‐2 is so different from other viruses and how regenerative medicine is poised to deliver new therapeutic opportunities to battle COVID‐19. We describe animal models that depict the mechanism of action for COVID‐19 and that may help identify new treatments. Additionally, organoid platforms that can recapitulate some of the physiological properties of human organ systems, such as the lungs and the heart, are discussed as potential platforms that may prove useful in rapidly screening new drugs and identifying at‐risk patients. This article critically evaluates some of the promising regenerative medicine‐based therapies for treating COVID‐19 and presents some of the collective technologies and resources that the scientific community currently has available to confront this pandemic.