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Aedes mosquitoes in the emerging threat of urban yellow fever transmission
Author(s) -
Gabiane Gaelle,
Yen PeiShi,
Failloux AnnaBella
Publication year - 2022
Publication title -
reviews in medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.06
H-Index - 90
eISSN - 1099-1654
pISSN - 1052-9276
DOI - 10.1002/rmv.2333
Subject(s) - chikungunya , yellow fever , dengue fever , aedes aegypti , transmission (telecommunications) , outbreak , virology , aedes , zika virus , case fatality rate , pandemic , vector (molecular biology) , chikungunya fever , biology , geography , environmental health , covid-19 , medicine , virus , ecology , population , disease , infectious disease (medical specialty) , recombinant dna , pathology , larva , engineering , biochemistry , electrical engineering , gene
This last decade has seen a resurgence of yellow fever (YF) in historical endemic regions and repeated attempts of YF introduction in YF‐free countries such as the Asia‐Pacific region and the Caribbean. Infected travellers are the main entry routes in these regions where competent mosquito vectors proliferate in appropriate environmental conditions. With the discovery of the 17D vaccine, it was thought that YF would be eradicated. Unfortunately, it was not the case and, contrary to dengue, chikungunya and Zika, factors that cotribute to YF transmission remain under investigation. Today, all the signals are red and it is very likely that YF will be the next pandemic in the YF‐free regions where millions of people are immunologically naïve. Unlike COVID‐19, YF is associated with a high case‐fatality rate and a high number of deaths are expected. This review gives an overview of global YF situation, including the non‐endemic Asia‐Pacific region and the Caribbean where Aedes aegypti is abundantly distributed, and also proposes different hypotheses on why YF outbreaks have not yet occurred despite high records of travellers importing YF into these regions and what role Aedes mosquitoes play in the emergence of urban YF.