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A water‐soluble, AIE‐active polyelectrolyte for conventional and fluorescence lifetime imaging of mouse neuroblastoma neuro‐2A cells
Author(s) -
Wang Yinan,
Yao Hongming,
Zhou Jian,
Hong Yuning,
Chen Bin,
Zhang Bolong,
Smith Trevor A.,
Wong Wallace W. H.,
Zhao Zujin
Publication year - 2018
Publication title -
journal of polymer science part a: polymer chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.768
H-Index - 152
eISSN - 1099-0518
pISSN - 0887-624X
DOI - 10.1002/pola.28943
Subject(s) - polyelectrolyte , fluorescence , chemistry , fluorescence lifetime imaging microscopy , biophysics , conjugated system , biocompatible material , intracellular , polymer , polymer chemistry , nanotechnology , materials science , organic chemistry , biomedical engineering , biochemistry , medicine , physics , quantum mechanics , biology
A new conjugated polyelectrolyte containing tetraphenylethene units in the backbone is synthesized and characterized. This polyelectrolyte is water‐soluble and exhibits aggregation‐induced emission (AIE) behavior. It is biocompatible and can be directly used in conventional and fluorescence lifetime imaging of mouse neuroblastoma neuro‐2A cells, providing useful information of cellular morphology and intracellular aggregation or motion. © 2018 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2018 , 56 , 672–680

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