
Synthesis and Antiprotozoal Profile of 3,4,5‐Trisubstituted Isoxazoles
Author(s) -
Rosa Fernanda Andreia,
Mendes de Souza Melo Samara,
Pianoski Karlos Eduardo,
Poletto Julia,
Santos Mariellen Guilherme,
Silva Michael Jackson Vieira,
LazarinBidóia Danielle,
Volpato Hélito,
Moura Sidnei,
Nakamura Celso Vataru
Publication year - 2021
Publication title -
chemistryopen
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.644
H-Index - 29
ISSN - 2191-1363
DOI - 10.1002/open.202100213
Subject(s) - antiprotozoal , cover (algebra) , isoxazole , chemistry , combinatorial chemistry , computer science , stereochemistry , engineering , biochemistry , mechanical engineering , in vitro
Invited for this month's cover picture is the group of Prof. Fernanda Andreia Rosa at the State University of Maringá (Brazil). The cover picture shows the contribution of the SINTHET research group to the synthesis and discovery of new antiprotozoal compounds. The synthetic methodology allowed the construction of 60 new isoxazole derivatives with structural variations on the 3‐, 4‐, and 5‐positions. The authors acknowledge Ms. Jeniffer do Nascimento Ascencio Camargo and Ms. Julia Caroline Manzano Willig for the Cover picture creation. Read the full text of their Full Paper at 10.1002/open.202100141.