Correcting inter‐scan motion artifacts in quantitative R 1 mapping at 7T

Purpose Inter‐scan motion is a substantial source of error inR 1estimation methods based on multiple volumes, for example, variable flip angle (VFA), and can be expected to increase at 7T whereB 1fields are more inhomogeneous. The established correction scheme does not translate to 7T since it requires a body coil reference. Here we introduce two alternatives that outperform the established method. Since they compute relative sensitivities they do not require body coil images. Theory The proposed methods use coil‐combined magnitude images to obtain the relative coil sensitivities. The first method efficiently computes the relative sensitivities via a simple ratio; the second by fitting a more sophisticated generative model. MethodsR 1maps were computed using the VFA approach. Multiple datasets were acquired at 3T and 7T, with and without motion between the acquisition of the VFA volumes.R 1maps were constructed without correction, with the proposed corrections, and (at 3T) with the previously established correction scheme. The effect of the greater inhomogeneity in the transmit field at 7T was also explored by acquiringB 1 +maps at each position. Results At 3T, the proposed methods outperform the baseline method. Inter‐scan motion artifacts were also reduced at 7T. However, at 7T reproducibility only converged on that of the no motion condition if position‐specific transmit field effects were also incorporated. Conclusion The proposed methods simplify inter‐scan motion correction ofR 1maps and are applicable at both 3T and 7T, where a body coil is typically not available. The open‐source code for all methods is made publicly available.