Effect of calcium phosphate (Ca‐P) coatings on trabecular bone response: A histological study
Author(s) -
Caulier H.,
van Der Waerden J. P. C. M.,
Paquay Y. C. G. J.,
Wolke J. G. C.,
Kalk W.,
Naert I.,
Jansen J. A.
Publication year - 1995
Publication title -
journal of biomedical materials research
Language(s) - English
Resource type - Journals
eISSN - 1097-4636
pISSN - 0021-9304
DOI - 10.1002/jbm.820290906
Subject(s) - calcium , materials science , trabecular bone , phosphate , biomaterial , biomedical engineering , dentistry , chemistry , medicine , osteoporosis , pathology , nanotechnology , biochemistry , metallurgy
The trabecular bone response to noncoated and fluorapatite (FA), hydroxyapatite (HA), and hydroxyapatite heattreated (HAHT) plasma‐sprayed coated implants was investigated in a goat animal model. Forty‐eight cylindrical implants were inserted into the trabecular bone of the lateral and medial femoral condyles of twelve goats according to a split plot design. After an implantation period of twelve weeks, the bone‐implant interface was evaluated histologically. Quantitative histomorphometrical measurements demonstrated a significant difference in bone contact between implants inserted in the lateral and medial condyles. In addition, a significant difference in bone apposition was observed between the coated and the uncoated implants. Finally, all Ca‐P coatings showed reduction in coating thickness. Measurements revealed that FA and HAHT showed less reduction in coating thickness than HA coating. Despite the coating reduction, the bone remained in close contact with the implant surface. © 1995 John Wiley & Sons, Inc.
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