Luminal surface fabrication for cardiovascular prostheses
Author(s) -
Deininger William D.,
Gabriel Stephen B.
Publication year - 1987
Publication title -
journal of biomedical materials research
Language(s) - English
Resource type - Journals
eISSN - 1097-4636
pISSN - 0021-9304
DOI - 10.1002/jbm.820210303
Subject(s) - materials science , polytetrafluoroethylene , fabrication , neointima , etching (microfabrication) , pillar , sputtering , morphology (biology) , smooth surface , biomedical engineering , hexagonal crystal system , composite material , nanotechnology , layer (electronics) , thin film , surgery , crystallography , stent , mechanical engineering , chemistry , restenosis , alternative medicine , pathology , biology , engineering , genetics , medicine
Methods to produce highly ordered, specific surface morphologies on polytetrafluoroethylene (PTFE Teflon) surfaces were developed. These methods included the use of photolithographic techniques for pattern definition and directed argon ion beam sputter etching to produce the desired surface morphology. Use of these techniques resulted in the formation of regular arrays of sharply defined hexagonal pillars with smooth, vertical walls with heights of up to 80 μm. Pillar height‐to‐width ratios ranged up to 5.2–1. Surface hole depths of up to approximately 80 μm were also obtained. These surface morphologies could have an important application in medicine for improving the patency of cardiovascular prostheses. This would be accomplished by creating a luminal surface in the implant which promotes the development of a healthy neointima lining.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom