Postoperative recurrence of Crohn's disease: Pathophysiology and prevention | Zendy

D'Haens Geert | Zendy; Rutgeerts Paul | Zendy

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Postoperative recurrence of Crohn's disease: Pathophysiology and prevention

Author(s) -

D'Haens Geert,

Rutgeerts Paul

Publication year - 1999

Publication title -

inflammatory bowel diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.932

H-Index - 146

eISSN - 1536-4844

pISSN - 1078-0998

DOI - 10.1002/ibd.3780050411

Subject(s) - medicine , crohn's disease , azathioprine , disease , ileum , pathophysiology , medical therapy , gastroenterology , surgery

Postoperative recurrence of Crohn's disease is often inevitable. Certain risk factors such as smoking, young age, and a perforating disease behavior have been identified. Patients running an enhanced risk should be treated with mesalamine or, with higher success rates, with azathioprine. An endoscopic evaluation of the neoterminal ileum 6 to 12 months after surgery provides relevant information predicting the further clinical course and can be used as a guide to adjust medical therapy.

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