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Electrochemical Sensing in Contact Lenses
Author(s) -
Liu Huixin,
Yan Xiaomei,
Gu Zhen,
Xiu Guangli,
Xiao Xinxin
Publication year - 2022
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.202100342
Subject(s) - amperometry , electrochemistry , contact lens , biosensor , analyte , nanotechnology , materials science , scope (computer science) , electrochemical gas sensor , chemistry , computer science , electrode , chromatography , optics , physics , programming language
Electrochemical sensors embedded in hydrogel‐based contact lenses provide valuable health‐related information, enabling non‐invasive and real‐time continuous monitoring. Recently, considerable progress has been made in tear based electrochemical sensors. The scope of reported analytes is continuously expanding. This review identifies key chemical biomarkers (including metabolites, ions, proteins) that can be electrochemically detected in tears. The working principles of i) amperometric enzymatic biosensors, ii) ion‐selective sensors for pH and ions, iii) voltammetric sensors and iv) affinity sensors are summarized. This review provides guidelines for the future development of contact lens based electrochemical sensors.