Air Pollution and Other Environmental Modulators of Cardiac Function | Zendy

Gorr Matthew W. | Zendy; Falvo Michael J. | Zendy; Wold Loren E. | Zendy

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Air Pollution and Other Environmental Modulators of Cardiac Function

Author(s) -

Gorr Matthew W.,

Falvo Michael J.,

Wold Loren E.

Publication year - 2017

Publication title -

comprehensive physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.207

H-Index - 80

ISSN - 2040-4603

DOI - 10.1002/cphy.c170017

Subject(s) - cardiovascular health , environmental health , air pollution , disease , hyperlipidemia , diabetes mellitus , pollution , air pollutants , epidemiology , cause of death , obesity , medicine , biology , endocrinology , ecology

ABSTRACT Cardiovascular disease (CVD) is the leading cause of death in developed regions and a worldwide health concern. Multiple external causes of CVD are well known, including obesity, diabetes, hyperlipidemia, age, and sedentary behavior. Air pollution has been linked with the development of CVD for decades, though the mechanistic characterization remains unknown. In this comprehensive review, we detail the background and epidemiology of the effects of air pollution and other environmental modulators on the heart, including both short‐ and long‐term consequences. Then, we provide the experimental data and current hypotheses of how pollution is able to cause the CVD, and how exposure to pollutants is exacerbated in sensitive states. Published 2017. Compr Physiol 7:1479‐1495, 2017.

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