Platelets and Their Interactions with Other Immune Cells | Zendy

Lam Fong W. | Zendy; Vijayan K. Vinod | Zendy; Rumbaut Rolando E. | Zendy

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Platelets and Their Interactions with Other Immune Cells

Author(s) -

Lam Fong W.,

Vijayan K. Vinod,

Rumbaut Rolando E.

Publication year - 2015

Publication title -

comprehensive physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.207

H-Index - 80

ISSN - 2040-4603

DOI - 10.1002/cphy.c140074

Subject(s) - platelet , immune system , inflammation , hemostasis , immunity , immunology , biology , microbiology and biotechnology , medicine

ABSTRACT Platelets are anucleate blood cells, long known to be critically involved in hemostasis and thrombosis. In addition to their role in blood clots, increasing evidence reveals significant roles for platelets in inflammation and immunity. However, the notion that platelets represent immune cells is not broadly recognized in the field of Physiology. This article reviews the role of platelets in inflammation and immune responses, and highlights their interactions with other immune cells, including examples of major functional consequences of these interactions. Published 2015. Compr Physiol 5:1265‐1280, 2015.

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