Adrenal Androgens and Androgen Precursors—Definition, Synthesis, Regulation and Physiologic Actions | Zendy

Turcu Adina | Zendy; Smith Joshua M. | Zendy; Auchus Richard | Zendy; Rainey William E. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Adrenal Androgens and Androgen Precursors—Definition, Synthesis, Regulation and Physiologic Actions

Author(s) -

Turcu Adina,

Smith Joshua M.,

Auchus Richard,

Rainey William E.

Publication year - 2014

Publication title -

comprehensive physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.207

H-Index - 80

ISSN - 2040-4603

DOI - 10.1002/cphy.c140006

Subject(s) - adina , pediatric endocrinology , reproductive endocrinology , medicine , gerontology , hormone , engineering , structural engineering , finite element method

Abstract The human adrenal produces more 19 carbon (C 19 ) steroids, by mass, than either glucocorticoids or mineralocorticoids. However, the mechanisms regulating adrenal C 19 steroid biosynthesis continue to represent one of the most intriguing mysteries of endocrine physiology. This review will discuss the C 19 steroids synthesized by the human adrenal and the features within the adrenal that allow production of these steroids. Finally, we consider the effects of these steroids in normal physiology and disorders of adrenal C 19 steroid excess. © 2014 American Physiological Society. Compr Physiol 4:1369‐1381, 2014.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research