Open AccessNew solenoidal microcoil NMR probe using zero‐susceptibility wire
Author(s) -
Kc Ravi,
Henry Ian D.,
Park Gregory H.J.,
Aghdasi Abdollah,
Raftery Daniel
Publication year - 2010
Publication title -
concepts in magnetic resonance part b: magnetic resonance engineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 32
eISSN - 1552-504X
pISSN - 1552-5031
DOI - 10.1002/cmr.b.20152
Subject(s) - microcoil , electromagnetic coil , solenoidal vector field , materials science , polydimethylsiloxane , homogeneity (statistics) , sensitivity (control systems) , analytical chemistry (journal) , bubble , nuclear magnetic resonance , chemistry , mechanics , composite material , electrical engineering , physics , chromatography , electronic engineering , statistics , mathematics , vector field , engineering
Abstract We present the construction and performance of a 20‐μL active volume probe that utilizes zero‐susceptibility wire for the detection transceiver coil and a 3.5‐mm outer diameter thin‐wall bubble flow cell to contain the sample. The probe shows good RF homogeneity, resolution, line shape, and sensitivity. The sensitivity and resolution of the 20‐μL probe was compared to those for several other coil configurations, including smaller detection volumes, a thin wire copper coil immersed in susceptibility matching perfluorocarbon FC‐43 (fluorinert) fluid, and a standard 5‐mm probe. In particular, the 1 H mass sensitivity, S m (SNR per micromole), was 3–4‐fold higher than that for the standard 5‐mm probe. Finally, the use of the zero‐susceptibility wire in smaller volume probes is discussed along with potential future improvements and applications. © 2010 Wiley Periodicals, Inc. Concepts Magn Reson Part B (Magn Reson Engineering) 37B: 13–19, 2010