Open AccessChemInform Abstract: Enone—Alkyne Reductive Coupling: A Versatile Entry to Substituted Pyrroles.
Author(s) -
Thompson Benjamin B.,
Montgomery John
Publication year - 2011
Publication title -
cheminform
Language(s) - English
Resource type - Journals
eISSN - 1522-2667
pISSN - 0931-7597
DOI - 10.1002/chin.201145098
Subject(s) - chemistry , alkyne , enone , ammonium acetate , oxidative cleavage , pyrrole , coupling (piping) , oxidative coupling of methane , combinatorial chemistry , organic chemistry , catalysis , mechanical engineering , high performance liquid chromatography , engineering
A three‐step procedure, consisting of the Ni‐catalyzed coupling of enones or enals with alkynes, oxidative cleavage and Paal—Knorr cyclization with ammonium acetate or anilines, allows the preparation of variously multisubstituted pyrrole derivatives.
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