Open AccessChemInform Abstract: Intramolecular Alkene Carboamination Reactions for the Synthesis of Enantiomerically Enriched Tropane Derivatives.
Author(s) -
Schultz Danielle M.,
Wolfe John P.
Publication year - 2011
Publication title -
cheminform
Language(s) - English
Resource type - Journals
eISSN - 1522-2667
pISSN - 0931-7597
DOI - 10.1002/chin.201138152
Subject(s) - chemistry , tropane , racemization , alkene , intramolecular force , optically active , stereochemistry , organic chemistry , combinatorial chemistry , catalysis
The attempt to transform noncyclic alkenyl substrates into tropane derivatives fails.The method proceeds generally without racemization and can be applied to the preparation of the MK‐801 analogue (XIII) in optically active form.
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